CD4 antibody (FITC)

Catalog No. ABIN317080

This Rat Monoclonal antibody specifically detects CD4 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CD4 antibody (FITC) (ABIN317080)

Target: CD4

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: RM4-5

Product Details anti-CD4 Antibody (FITC)

Specificity: This antibody detects CD4, a 55 kDa protein also known as Ly-4 and L3T4. This antibody Clone RM4-5 is useful for in vitro blocking of ligand binding, as well as in vitro CD4+ T cell depletions.

Characteristics: Synonyms: T4/Leu-3, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: BALB/c mouse thymocytes.

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing lowaffinity Fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: CD4 is a single chain transmembraneous glycoprotein which belongs to the immunoglobulin superfamily, and is primarily expressed on peripheral blood monocytes and tissue macrophages. CD4 is also expressed on a subpopulation of regulatory T cells (CD4+CD25+), which play a key role in the maintenance of self tolerance.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Gene ID: 12504

UniProt: P06332

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events